INSULIN TIMINGS!

Many of our Patients are on insulin. The most common reason why insulin does not control blood sugar is that we do not understand the dynamics of insulin. Here I have put a concise format so that everybody can understand which insulins has to be taken when....

Insulin preparation	Generic name	Onset	Peak	Duration
Rapid-acting	Insulin Aspart	5-10 minutes	1-3 hrs	3-5 hrs
	Insulin Lispro	< 15 minutes	½-1½ hrs	2-4 hrs
	Insulin Glulisine	< 15 minutes	½-1½ hrs	1-2½ hrs
Short-acting	Regular	½-1 hr	2-3 hrs	3-6 hrs
Intermediate- acting	NPH	2-4 hrs	4-10 hrs	10-16 hrs
Long-acting	Insulin Glargine	1 hr	No peak	24 hrs
	Detemir	1-2 hrs	No peak	6-23 hrs, depending on dose
Combinations	70% NPH +30% Regular	½-1 hr	There are2 peaks: 2-3 hrs &4-10 hrs	10-16 hrs
	70% Aspart Protamine +30% Aspart	5-10 minutes	There are2 peaks: 1-3 hrs &4-10 hrs	10-16 hrs
	50% Lispro Protamine +50% Lispro	< 15 minutes	There are2 peaks: ½-1½ hrs &4-10 hrs	10-16 hrs
	75% Lispro Protamine +25% Lispro	< 15 minutes	There are2 peaks: ½-1½ hrs &4-10 hrs	10-16 hrs

Feel free to tell me if this helps!!