Showing posts with label DIABETES DRUGS. Show all posts
Showing posts with label DIABETES DRUGS. Show all posts

17 January, 2019

DIABETES PILLS DON’T WORK OVERTIME !!


The credit for this post goes to Mrs. X. She inspired me to write this small post as well resuscitate my blog which has not been updated very frequently off late.

Mrs.X is a cheerful 60+ lady who has been managing her blood sugars decently well. She is on a small dose of Glimepiride and Metformin. She checks her blood sugars regularly. Doctor reviews are perfect and no complications so far. In short she is the ideal patient every Doctor would aspire for.
This cheerful lady went about doing her chores gleefully till that day…

That day…. She got up in the morning as usual and went to the bathroom. Her absentminded maid had forgotten to scrub the bathroom floor. As soon as Mrs.X set foot on the bathroom floor she went sliding to other corner of the bathroom. Her unplanned inertia was cut short by the wall where she had hit her knee. With some help from her daughter she managed to settle down on the bed with liberal supplies of ointments, thailams and how water bag.

14 August, 2014

LATEST TREND - SEND OUT EXCESS SUGAR IN URINE!

New member of the squad against Diabetes!

Canagliflozin 

Canagliflozin is a newest member in treatment of Type 2 Diabetes. This drug can be used as adjuvant to Diet & Exercise.

Canagliflozin inhibits Sodium Glucose Transport protein Sub type 2. This protein is responsible for reabsoption of sugar in the kidneys.


By stopping the activity of Sodium Glucose Transport Protein -2 (SGLT-2) will result in loss of glucose in urine. Canagliflozin can help lose about 80-120mg/dl sugar. Additional benefits are better control of Hypertension due to osmotic diuresis and weight loss. 

Half life of Canagliflozin is upto 12hours, Hence a twice daily dosage is preferred.

Canagliflozin comes in  the strengths of 50mg and 150mg

A recent welcome addition is introduction of Invokamet (Canagliflozin + Metformin)

The available combinations are 

Canagliflozin 50 mg + Metformin 500mg
Canagliglozin 50mg + Metformin 1000mg
Canagliflozin 150 mg + Metformin 500mg
Canagliglozin 150mg + Metformin 1000mg

Since most of our patients require twice daily metformin this combination will help give better sugar control. 1 Tablet with advantage of two drugs. 
This drug may help patients attain a better control of blood sugars.
Chances of hypoglycemia are relatively less

This Drug cannot be used in patients with Renal failure, Hypotension and Type 1 Diabetes!

Some patients ( ~5%) may experience the side effects like Female genital mycotic infections, Urinary tract infections and increased urination.

My previous write up about Canagliflozin - CLICK HERE!

This drug being marketed by Johnson & Johnson is expected to come to India soon.

More in news from Johnson & Johnson - JNJ

Dr.Riyaz Sheriff
R.S. Clinic


09 July, 2013

VOICES FOR PIOGLITAZONE

Pioglitazone finally had some supporters.

Here is an article from HINDU

Govt should reconsider ban on diabetes drug, say doctors | Business Line

INDIAN EXPRESS

Ban on anti-diabetes drug pioglitazone shocks doctors

ZEE NEWS

Doctors flay blanket ban on diabetes drug Pioglitazone

MUMBAI MIRROR

Choice before diabetics: Painful insulin or costly but less-effective drugs

SAKAL TIMES

Diabetes expert demands withdrawal of ban on pioglitazone


with the way our cost of medication is going up drugs like these should not be banned. I sincerely feel Pioglitazone needs a second chance in the Indian market.

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